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KMID : 1149220000080010329
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Korean Journal of Oriental Medical Prescription
2000 Volume.8 No. 1 p.329 ~ p.342
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A Experimental Study on the Citri Reticulatae Viride Pericarpium( I )
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Kang Sung-Yung
Jung Hyun-Woo
Lee Won-Seok
Han Jong-Hyun
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Abstract
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Citri Reticulatae Viride Pericarpium(CRVP) is being used to regulate the flow of Q(氣) However, the mechanism of it’s pharmacological actions is not well understood. The purpose of this research was to investigate effects of CRVP contractil response of isolated on abdominal and femoral artery in rabbits and renal artery in pigs. 1. Abdominal artery was relaxed by CRVP in a dose-dependent manner. 2. Femoral artery was relaxed by CRVP in a dose-dependent manner 3. Pretreatment with methylene blue and indomethacin did not inhibited CRVP induced relax in abdominal artery and femoral artery. 4. Renal artery was relaxed by H₂O fraction in a dose-dependent manner, 5. Pretreatment with regitine inhibited H₂O fraction(CRVP) induced relax in renal artery in a dose-dependent manner. 6. Renal artery was not relaxed by hexane fraction(CRVP) in a dose-dependent manner. 7. Pretreatment with regitine was relaxed by methylene chloride(MC)(CRVP) and H₂O fraction in a 0.5 ug/ml.
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